Description

2-Propynamide,n-(4-Fluorophenyl)-(9Ci) is a specialized fluorinated organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where the introduction of fluorine atoms and acetylene functionality is crucial for modulating biological activity and material properties. It is primarily needed by research institutions and industrial R&D departments focused on medicinal chemistry, material science, and the synthesis of complex organic molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system disorders and cancer.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the fluorophenyl group enhances bioavailability and environmental stability.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the creation of specialized polymers and advanced organic materials with tailored electronic or optical properties.
• Chemical Biology Probe: Utilized in click chemistry and bioconjugation strategies for labeling biomolecules and studying biological pathways due to its alkyne functionality.
• Organic Synthesis Reagent: Employed in palladium-catalyzed cross-coupling reactions (e.g., Sonogashira coupling) to construct complex molecular architectures.

Basic Information

Product Name	2-Propynamide,n-(4-Fluorophenyl)-(9Ci)
CAS No.	446302-33-6
Molecular Formula	C9H6FNO
Molecular Weight	163.15 g/mol
Synonyms	N-(4-Fluorophenyl)propiolamide; 4-Fluorophenylpropiolamide; p-Fluorophenylpropiolamide; Propiolic acid 4-fluoroanilide; (4-Fluorophenyl)propiolamide; 2-Propynamide, N-(4-fluorophenyl)-; 446302-33-6
EINECS	Contact for details

Quality Control

Our 2-Propynamide,n-(4-Fluorophenyl)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.