Description

Potassium Cyclohexyltrifluoroborate is a versatile organoboron reagent widely used in modern synthetic chemistry. This compound is a stable, crystalline salt that serves as a crucial source of the cyclohexyl group in various cross-coupling reactions. It is particularly valuable for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable and efficient methods for C-C bond formation. Its stability and handling characteristics make it a preferred alternative to more sensitive organometallic reagents.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for introducing the cyclohexyl moiety into biaryl and heteroaryl systems, essential for pharmaceutical intermediate synthesis.
• Agrochemical Active Ingredient Development: Used in the synthesis of novel compounds with potential herbicidal or insecticidal activity.
• Material Science & Liquid Crystal Research: Employed in the creation of organic semiconductors and liquid crystal molecules where the cyclohexyl group influences physical properties.
• Medicinal Chemistry & Drug Discovery: Facilitates the rapid exploration of structure-activity relationships (SAR) by enabling efficient diversification of core scaffolds.
• Catalyst & Ligand Synthesis: Used as a building block for constructing sophisticated phosphine or N-heterocyclic carbene (NHC) ligands.
• Process Chemistry & Scale-up: Offers advantages in safety and purity for the large-scale manufacturing of fine chemicals and active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Potassium Cyclohexyltrifluoroborate
CAS No.	446065-11-8
Molecular Formula	C6H11BF3K
Molecular Weight	190.06 g/mol
Synonyms	Potassium (Cyclohexyl)trifluoroborate; Cyclohexyltrifluoroborate Potassium Salt; Cyclohexyl-BF3K; Potassium Cyclohexyl-Trifluoro-Borate; Potassium Trifluoro(cyclohexyl)borate; Cyclohexyl Potassium Trifluoroborane; K-cyclohexyltrifluoroborate; Cyclohexylboronic Acid Trifluoroborate Potassium Salt
EINECS	Contact for details

Quality Control

Our Potassium Cyclohexyltrifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 19F) and HPLC analysis, to ensure high purity and consistent performance in sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to ambient moisture. Optimal storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (Potentiometric Titration)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.