Description

(R,R,R)-1-(3,5-Dioxa-4-Phosphacyclohepta[2,1-A:3,4-A′]Dinaphthalen-4-Yl)-2,5-Diphenylpyrrolidine is a high-value, chiral phosphorus-nitrogen ligand with the CAS registry number 444667-33-8. This compound is critically important for enabling highly selective and efficient catalytic transformations in asymmetric synthesis. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of novel active ingredients and advanced intermediates.

Application

• Asymmetric Catalysis: Serving as a privileged chiral ligand for transition metal-catalyzed reactions, including hydrogenation, hydroformylation, and cross-coupling.
• Pharmaceutical Intermediate Synthesis: Enabling the production of enantiomerically pure drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Facilitating the development of chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Material Science: Potential use in the synthesis of chiral polymers or advanced functional materials.
• Academic & Process Chemistry: A key tool for methodological development in organic synthesis and scale-up process optimization.

Basic Information

Product Name	(R,R,R)-1-(3,5-Dioxa-4-Phosphacyclohepta[2,1-A:3,4-A′]Dinaphthalen-4-Yl)-2,5-Diphenylpyrrolidine
CAS No.	444667-33-8
Molecular Formula	C34H28NO2P
Molecular Weight	513.57 g/mol
Synonyms	(R,R,R)-2,5-Diphenyl-1-(4H-1,3,2-benzodioxaphosphinin-4-yl)pyrrolidine; (R,R,R)-DuanPhos; (R,R,R)-1-(4H-Benzo[d][1,3,2]dioxaphosphinin-4-yl)-2,5-diphenylpyrrolidine; (R,R,R)-1-(1,3,2-Benzodioxaphosphol-4-yl)-2,5-diphenylpyrrolidine; (4R,4'R,5'R)-4-(2,5-Diphenylpyrrolidin-1-yl)-4H-1,3,2-benzodioxaphosphinine; DuanPhos Ligand; Chiral Phosphorus-Nitrogen Bidentate Ligand
EINECS	Contact for details

Quality Control

Our (R,R,R)-1-(3,5-Dioxa-4-Phosphacyclohepta[2,1-A:3,4-A′]Dinaphthalen-4-Yl)-2,5-Diphenylpyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (argon or nitrogen) is recommended. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.