Description

2-(3-Aminopropoxy)Benzonitrile is a versatile aromatic nitrile derivative featuring a terminal amino group on a propoxy linker. This bifunctional structure makes it a valuable pharmaceutical intermediate and organic building block for the synthesis of more complex molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Ligand and Catalyst Preparation: Serves as a precursor for creating chelating ligands and organocatalysts used in asymmetric synthesis.
• Polymer Modification: Functional monomer for introducing cyano and amino groups into polymer backbones to alter material properties.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized colorants and imaging agents.
• Cross-coupling Reactions: Useful substrate in palladium-catalyzed reactions like Suzuki-Miyaura or Buchwald-Hartwig amination for creating biaryl structures.

Basic Information

Product Name	2-(3-Aminopropoxy)Benzonitrile
CAS No.	444574-75-8
Molecular Formula	C10H12N2O
Molecular Weight	176.22 g/mol
Synonyms	2-(3-Aminopropoxy)benzonitrile; Benzonitrile, 2-(3-aminopropoxy)-; 3-(2-Cyanophenoxy)propylamine; 2-(3-Aminopropoxy)phenyl cyanide; 2-Cyanophenyl 3-aminopropyl ether; 3-(2-Cyanophenoxy)-1-propanamine; 1-Amino-3-(2-cyanophenoxy)propane
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Aminopropoxy)Benzonitrile is manufactured under a cGMP-compliant quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.