Description

(D-Ala2)-Gastric Inhibitory Polypeptide (Human) is a synthetic, biologically active peptide analog of the human gastric inhibitory polypeptide (GIP). This compound is of significant value in metabolic and endocrine research due to its role in glucose-dependent insulin secretion and fat metabolism. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on diabetes, obesity, and metabolic syndrome studies.

Application

• Pharmacological Research: Used as a key tool in studying the physiology and pathophysiology of the incretin system.
• Drug Discovery: Serves as a reference standard and lead compound in the development of novel GIP receptor agonists or antagonists for metabolic diseases.
• In Vitro & In Vivo Studies: Applied in cell-based assays and animal models to investigate insulin secretion, β-cell function, and lipid metabolism.
• Biochemical Analysis: Utilized in receptor binding studies, signal transduction pathway analysis, and enzyme-linked immunosorbent assays (ELISAs).
• Quality Control: Acts as a certified reference material (CRM) for the analytical testing and validation of related peptide-based therapeutics.

Basic Information

Product Name	(D-Ala2)-Gastric Inhibitory Polypeptide (Human)
CAS No.	444073-04-5
Molecular Formula	C225H358N64O69S
Molecular Weight	4984.7 g/mol
Synonyms	(D-Ala2)GIP(human); GIP (1-42), human, D-Ala2-; D-Ala2-GIP; Gastric Inhibitory Polypeptide (1-42) (human) with D-Alanine at position 2; Glucose-dependent Insulinotropic Polypeptide, D-Ala2 analog; Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-Arg-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Asn-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln
EINECS	Contact for details

Quality Control

Our (D-Ala2)-Gastric Inhibitory Polypeptide (Human) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing purity, peptide content, and solvent residues are provided to ensure compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Composition	Within ±10% of theoretical values
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.