Description

3-Oleoylestrone-D4 is a deuterated derivative of the endogenous estrogen metabolite, oleoylestrone. This compound is of significant value as a high-purity, stable isotope-labeled internal standard for quantitative bioanalytical research. It is primarily required by analytical laboratories, pharmaceutical R&D departments, and CROs (Contract Research Organizations) engaged in advanced mass spectrometry-based assays, particularly for the precise measurement of steroid hormones and their fatty acid esters in complex biological matrices.

Application

• Internal Standard for LC-MS/MS: Serves as a critical, non-interfering reference compound for the accurate quantification of oleoylestrone and related metabolites in pharmacokinetic and metabolomic studies.
• Endocrinology Research: Enables precise investigation into the role of lipoidal estrogens and their metabolic pathways in various physiological and pathological states.
• Biomarker Assay Development: Used in the development and validation of highly specific and sensitive clinical diagnostic methods for hormone-related conditions.
• Drug Metabolism and Pharmacokinetics (DMPK): Facilitates the study of the absorption, distribution, metabolism, and excretion (ADME) of steroidal compounds and their lipoconjugates.
• Quality Control in Reference Material Production: Acts as a calibrant or system suitability standard in the manufacturing of certified reference materials (CRMs) for clinical laboratories.

Basic Information

Item	Details
Product Name	3-Oleoylestrone-D4
CAS No.	443791-75-1
Molecular Formula	C36H52D4O3
Molecular Weight	548.86 g/mol (approx.)
Synonyms	Oleoyl Estrone-d4; 3-Oleoyloxyestra-1,3,5(10)-trien-17-one-d4; Estrone 3-oleate-d4; Deuterated Oleoylestrone; [2H4]-3-Oleoylestrone; 17-Oxoestra-1,3,5(10)-trien-3-yl (9Z)-octadec-9-enoate-d4; Internal Standard for Oleoylestrone
EINECS	Contact for details

Quality Control

Our 3-Oleoylestrone-D4 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including NMR, HPLC, and mass spectrometry, to confirm identity, isotopic purity (≥98% D), and chemical purity (≥95% by HPLC). A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC-MS)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (by NMR)	≥ 95%
Solubility	Soluble in DMSO, DMF, chloroform

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.