Description

(3-Bromo-2,6-Dimethoxy-4-Pyridyl)Di-3,5-Xylylphosphine Oxide is a high-value, specialty organophosphorus ligand designed for advanced catalytic transformations. This compound matters for its role in facilitating challenging cross-coupling and other metal-catalyzed reactions, offering researchers and process chemists a sophisticated tool for constructing complex molecular architectures. It is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate Synthesis: As a key ligand in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) for constructing biaryl and heteroaryl structures in drug discovery and development.
• Agrochemical Research: Enabling the synthesis of novel, complex active ingredients through efficient catalytic cycles in process chemistry.
• Advanced Materials Development: Facilitating the creation of organic electronic materials, ligands for metal-organic frameworks (MOFs), and specialty polymers via controlled catalytic processes.
• Catalyst Ligand Screening: Serving as a critical component in high-throughput screening libraries for identifying new catalytic systems in academic and industrial research.
• Process Chemistry Optimization: Improving yield, selectivity, and efficiency in scale-up syntheses for fine chemical and active pharmaceutical ingredient (API) manufacturing.

Basic Information

Product Name	(3-Bromo-2,6-Dimethoxy-4-Pyridyl)Di-3,5-Xylylphosphine Oxide
CAS No.	442686-32-0
Molecular Formula	C₂₈H₂₇BrNO₃P
Molecular Weight	536.40 g/mol
Synonyms	Di(3,5-dimethylphenyl)(3-bromo-2,6-dimethoxy-4-pyridinyl)phosphine oxide; (3-Bromo-2,6-dimethoxy-4-pyridinyl)bis(3,5-dimethylphenyl)phosphine oxide; 3-Bromo-2,6-dimethoxy-4-pyridyldi(3,5-xylyl)phosphine oxide; BR-DMPO Ligand; BR-DMPPO; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Every batch of (3-Bromo-2,6-Dimethoxy-4-Pyridyl)Di-3,5-Xylylphosphine Oxide is produced and tested under strict quality management protocols to ensure consistency and reliability for critical research and development applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed batch-specific data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be stored away from light. Keep container tightly sealed under an inert atmosphere if long-term storage is required to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.