Description

Cyclohexanecarbonitrile, 5-Methyl-2-(1-Methylethyl)-, (1R,2S,5R)- (9Ci) is a high-purity, stereochemically defined nitrile derivative of menthol. This compound serves as a critical chiral intermediate and building block in advanced organic synthesis, enabling the production of complex molecules with precise stereochemistry. It is primarily required by pharmaceutical R&D and fine chemical manufacturers for applications in drug discovery, agrochemicals, and fragrance chemistry.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring specific stereoisomers.
• Agrochemical Synthesis: Building block for developing advanced pesticides and herbicides with enhanced efficacy and selectivity.
• Fragrance & Flavor Chemistry: Precursor for creating novel, high-value aroma chemicals and flavor compounds with minty or cooling characteristics.
• Asymmetric Catalysis Research: Used as a ligand precursor or a test substrate in the development of new chiral catalysts and synthetic methodologies.
• Material Science: Intermediate for specialty polymers and advanced materials where the nitrile functionality and rigid cyclohexane structure are beneficial.
• Academic & Industrial R&D: Serves as a standard or starting material in research laboratories for exploring new chemical transformations.

Basic Information

Product Name	Cyclohexanecarbonitrile, 5-Methyl-2-(1-Methylethyl)-, (1R,2S,5R)- (9Ci)
CAS No.	439924-29-5
Molecular Formula	C11H19N
Molecular Weight	165.28 g/mol
Synonyms	(1R,2S,5R)-5-Methyl-2-(1-methylethyl)cyclohexanecarbonitrile; (-)-Menthyl cyanide; (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanecarbonitrile; L-Menthone cyanohydrin derivative; (1R,2S,5R)-Menthane-1-carbonitrile; Chiral menthone nitrile; (1R,2S,5R)-p-Menthane-1-carbonitrile
EINECS	Contact for details

Quality Control

Our Cyclohexanecarbonitrile, 5-Methyl-2-(1-Methylethyl)-, (1R,2S,5R)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and GC, to ensure high chemical and enantiomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Chiral Purity (Enantiomeric Excess)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.