Description

Acetamide, 2-[[(1,1-Dimethylethyl)Diphenylsilyl]Oxy]- is a specialized organosilicon-protected intermediate of significant value in advanced organic synthesis. This compound matters because it provides a robust and selective protecting group for sensitive hydroxyl functionalities, enabling complex multi-step reactions in demanding chemical environments. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and complex natural products.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the development and production of advanced pesticides, herbicides, and plant growth regulators.
• Fine Chemical Production: Serves as a critical precursor for synthesizing specialty chemicals, flavors, and fragrances.
• Academic & Industrial Research: A valuable tool in methodological development and exploratory chemistry for creating novel molecular architectures.
• Peptide & Carbohydrate Chemistry: Employed for the temporary protection of hydroxyl groups during the synthesis of complex biomolecules.
• Material Science Precursor: Potential use in the synthesis of functionalized silanes for surface modification and advanced material development.

Basic Information

Product Name	Acetamide, 2-[[(1,1-Dimethylethyl)Diphenylsilyl]Oxy]-
CAS No.	439692-26-9
Molecular Formula	C20H27NO2Si
Molecular Weight	341.52 g/mol
Synonyms	2-[(tert-Butyldiphenylsilyl)oxy]acetamide; 2-(tert-Butyldiphenylsiloxy)acetamide; N-[2-(tert-Butyldiphenylsilyloxy)acetyl]amine; Acetamide, 2-[(tert-butyldiphenylsilyl)oxy]-; TBDPS-protected glycolamide; 2-(TBDPSO)acetamide; Glycolamide, 2-O-(tert-butyldiphenylsilyl)-; tert-Butyldiphenylsilyl glycolate amide
EINECS	Contact for details

Quality Control

Our Acetamide, 2-[[(1,1-Dimethylethyl)Diphenylsilyl]Oxy]- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistent performance as a synthetic intermediate. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.