Description

Acetonitrile, [(1R,4S)-1,3,3-Trimethylbicyclo[2.2.1]hept-2-ylidene]-, (2Z)- (9Ci) is a specialized chiral chemical building block featuring a rigid norbornane-derived framework. This compound matters for its unique stereochemistry and structural complexity, making it a valuable intermediate in advanced organic synthesis and pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Synthesis: Utilized as a sophisticated ligand precursor or building block in catalytic asymmetric reactions to induce high enantioselectivity.
• Agrochemical Research: Serves as an intermediate in the synthesis of advanced, stereochemically-defined pesticides and herbicides.
• Material Science: Potential monomer or additive for creating polymers with specific optical or structural properties due to its rigid, bulky group.
• Academic & Industrial R&D: Employed in methodological studies and the discovery of new chemical reactions and processes.
• Fine Chemical Production: Used in the multi-step synthesis of complex fragrances, flavors, and other high-value specialty chemicals.

Basic Information

Product Name	Acetonitrile, [(1R,4S)-1,3,3-Trimethylbicyclo[2.2.1]hept-2-ylidene]-, (2Z)- (9Ci)
CAS No.	439689-21-1
Molecular Formula	C₁₂H₁₇N
Molecular Weight	175.27 g/mol
Synonyms	(2Z)-[(1R,4S)-1,3,3-Trimethylbicyclo[2.2.1]hept-2-ylidene]acetonitrile; (1R,4S)-1,3,3-Trimethyl-2-((Z)-cyanomethylene)norbornane; (Z)-[(1R,4S)-1,3,3-Trimethyl-2-norbornylidene]acetonitrile; (Z)-2-((1R,4S)-1,3,3-Trimethylbicyclo[2.2.1]heptan-2-ylidene)acetonitrile; Chiral Norbornylidene Acetonitrile Derivative; Fenchylidene Acetonitrile Derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with typical purity levels suitable for research and development applications. Certificates of Analysis (COA) detailing identity, purity (by GC or HPLC), and chiral purity are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. Keep away from strong oxidizing agents and strong acids.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.