Description

(2-Cyano-Benzyl)-Carbamic Acid tert-Butyl Ester is a protected amine derivative, specifically a Boc-protected ortho-cyanobenzylamine, which serves as a critical building block in advanced organic synthesis. This compound matters because it provides a versatile and stable intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and other specialty molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Peptidomimetic Chemistry: Used in the construction of non-peptide scaffolds that mimic the structure and function of peptides.
• Ligand and Receptor Probe Development: Serves as a precursor for creating specialized chemical probes used in biochemical and pharmacological assays.
• Agrochemical Synthesis: Employed in the research and development of new pesticides and herbicides, leveraging its functional group versatility.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of advanced polymers with specific optical or electronic properties.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	(2-Cyano-Benzyl)-Carbamic Acid tert-Butyl Ester
CAS No.	439118-51-1
Molecular Formula	C13H16N2O2
Molecular Weight	232.28 g/mol
Synonyms	tert-Butyl N-[(2-cyanophenyl)methyl]carbamate; Boc-2-Cyanobenzylamine; N-Boc-2-Cyanobenzylamine; N-(tert-Butoxycarbonyl)-2-cyanobenzylamine; 2-[(tert-Butoxycarbonyl)amino]methyl]benzonitrile; (2-Cyanobenzyl)carbamic Acid 1,1-Dimethylethyl Ester; Carbamic acid, N-[(2-cyanophenyl)methyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our (2-Cyano-Benzyl)-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.