Description

n-[4-(1-Hexynyl)Phenyl]Methanesulfonamide is a specialized organic building block featuring a terminal alkyne and a methanesulfonamide group on a phenyl ring. This unique bifunctional structure makes it a valuable intermediate for the synthesis of more complex molecules via click chemistry and cross-coupling reactions. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active compounds and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in medicinal chemistry for the development of new drug candidates, particularly through Huisgen 1,3-dipolar cycloaddition (click chemistry).
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its alkyne moiety for structural diversification.
• Material Science: Acts as a monomer or cross-linking agent in the development of advanced polymers and functional materials with tailored properties.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and tags for studying biological processes and protein interactions.
• Ligand Synthesis: Useful for creating specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to global clients.

Basic Information

Product Name	n-[4-(1-Hexynyl)Phenyl]Methanesulfonamide
CAS No.	439097-42-4
Molecular Formula	C13H17NO2S
Molecular Weight	251.34 g/mol
Synonyms	4-(1-Hexyn-1-yl)-N-(methylsulfonyl)aniline; Methanesulfonamide, N-[4-(1-hexynyl)phenyl]-; N-(4-Hex-1-ynylphenyl)methanesulfonamide; 1-Hexyne, 1-[4-[(methylsulfonyl)amino]phenyl]-; p-(1-Hexynyl)phenyl methanesulfonamide
EINECS	Contact for details

Quality Control

Every batch of n-[4-(1-Hexynyl)Phenyl]Methanesulfonamide is produced and tested under strict quality management protocols to ensure consistency and purity for critical R&D and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality systems are designed to support development from milligram to kilogram scale with reliable traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.