Description

N,n-Bis(tert-Butoxycarbonyl)-o-Phenylenediamine is a high-purity, protected diamine derivative primarily used as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile Boc-protected intermediate, enabling the controlled introduction of an o-phenylenediamine moiety into complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for drug discovery and fine chemical production.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of heterocyclic compounds and kinase inhibitors.
• Agrochemical Synthesis: Used in the production of advanced fungicides, herbicides, and plant growth regulators that require a protected diamine functionality.
• Peptide Mimetics & Linker Chemistry: Serves as a precursor for creating peptide-like structures and as a spacer/linker in bioconjugation and prodrug development.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for the synthesis of specialty polyamides, polyimides, and other high-performance polymers.
• Organic Synthesis Reagent: A versatile reagent for constructing complex nitrogen-containing heterocycles like benzimidazoles and quinoxalines under mild deprotection conditions.
• Research & Development: Critical for academic and industrial R&D labs focused on medicinal chemistry and novel synthetic methodology development.

Basic Information

Product Name	N,n-Bis(tert-Butoxycarbonyl)-o-Phenylenediamine
CAS No.	438533-54-1
Molecular Formula	C₁₆H₂₄N₂O₄
Molecular Weight	308.37 g/mol
Synonyms	1,2-Bis[(tert-butoxycarbonyl)amino]benzene; N,N'-Di-Boc-o-phenylenediamine; o-Phenylenediamine, N,N'-bis(tert-butoxycarbonyl)-; N,N'-Di-tert-butoxycarbonyl-1,2-diaminobenzene; Boc₂-o-Phenylenediamine; 1,2-Diaminobenzene N,N'-bis-Boc derivative; N,N'-Bis(Boc)-1,2-benzenediamine; DiBoc-o-Phenylenediamine
EINECS	Contact for details

Quality Control

Our N,n-Bis(tert-Butoxycarbonyl)-o-Phenylenediamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to guarantee consistency and traceability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.