Description

tert-Butyl 3-Amino-2-Phenylpropylcarbamate is a versatile Boc-protected amino acid derivative, serving as a critical chiral building block in organic synthesis. Its primary value lies in enabling the controlled synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. This intermediate is essential for research and production teams in the pharmaceutical, agrochemical, and advanced material sectors who require high-purity, structurally defined compounds for their synthetic pathways.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of peptide-based drugs, enzyme inhibitors, and other bioactive molecules.
• Agrochemical Research: Building block for developing novel pesticides and herbicides with specific stereochemical configurations.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis (SPPS) to introduce protected amino functionalities.
• Chemical Biology: Valuable for creating molecular probes and labeled compounds for biological studies.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing custom fine chemicals.
• Academic Research: Employed in university and institutional labs for methodological development in asymmetric synthesis.

Basic Information

Product Name	tert-Butyl 3-Amino-2-Phenylpropylcarbamate
CAS No.	437708-57-1
Molecular Formula	C14H22N2O2
Molecular Weight	250.34 g/mol
Synonyms	Boc-3-Amino-2-phenylpropylamine; tert-Butyl N-(3-Amino-2-phenylpropyl)carbamate; 3-Amino-2-phenylpropylcarbamic acid tert-butyl ester; 1-[(tert-Butoxycarbonyl)amino]-3-amino-2-phenylpropane; (R/S)-tert-Butyl 3-amino-2-phenylpropylcarbamate; 2-Phenyl-1,3-propanediamine, N1-Boc-protected; N-Boc-1,3-diamino-2-phenylpropane
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Amino-2-Phenylpropylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (or as specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.