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1,1Bis[(2S,5S)-2,5-Diethylphospholano]Ferrocene, Min. 97% CAS NO 436863-50-2


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CAS No.:436863-50-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,1Bis[(2S,5S)-2,5-Diethylphospholano]Ferrocene, Min. 97% is a high-purity, chiral ferrocenyl phosphine ligand, a critical component in asymmetric catalysis. Its value lies in enabling highly enantioselective transformations, crucial for producing single-isomer pharmaceutical intermediates and fine chemicals. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-performance ligands for hydrogenation and cross-coupling reactions.

Application

  • As a chiral ligand in asymmetric hydrogenation reactions for pharmaceutical synthesis.
  • Catalyst component for the enantioselective synthesis of amino acids and their derivatives.
  • Use in asymmetric cross-coupling reactions to construct chiral carbon-carbon bonds.
  • Key reagent in the production of enantiomerically pure agrochemicals and flavors/fragrances.
  • Research and development of novel catalytic processes in academic and industrial laboratories.
  • Process development and scale-up for the manufacture of chiral active pharmaceutical ingredients (APIs).

Basic Information

Product Name 1,1Bis[(2S,5S)-2,5-Diethylphospholano]Ferrocene, Min. 97%
CAS No. 436863-50-2
Molecular Formula C24H38FeP2
Molecular Weight 444.34 g/mol
Synonyms (S,S)-1,1'-Bis(2,5-diethylphospholano)ferrocene; Josiphos SL-J009-1; (S,S)-2,2'-Bis(2,5-diethylphospholanyl)-1,1'-biferrocene; (2S,5S)-1,1'-Bis(2,5-diethylphospholano)ferrocene; (S,S)-Diethyl-PhanePhos; (S,S)-Et-FerroPhos; Chiral ferrocenyl diphosphine ligand; SL-J009-1 Ligand
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Quality Control

Our 1,1Bis[(2S,5S)-2,5-Diethylphospholano]Ferrocene is manufactured under strict quality systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is analyzed to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) documenting these results are available upon request, providing full transparency and supporting cGMP development work.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry place. This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and performance.

Specification

Item Specification
Appearance Orange to red-brown solid
Identification (IR) Conforms to structure
Purity (HPLC) Min. 97.0%
Enantiomeric Excess (Chiral HPLC) Min. 99.0% ee
Solubility Soluble in common organic solvents (e.g., Toluene, THF, DCM)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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