Description

(3S)-(-)-3-(1-Methyl-1H-Indol-3-Yl)Butanenitrile is a chiral, non-natural amino acid derivative featuring a substituted indole moiety, serving as a critical chiral building block in advanced organic synthesis. This high-purity intermediate is essential for the development of novel pharmaceuticals and bioactive compounds, offering precise stereochemical control. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery.
• Asymmetric Synthesis: Used as a building block in the synthesis of complex, stereochemically defined molecules for medicinal chemistry and catalyst development.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Biochemical Research: Employed in the study of enzyme inhibitors and receptor ligands due to its structural similarity to tryptophan derivatives.
• Fine Chemical Production: Utilized in the custom synthesis of specialty chemicals, flavors, and fragrances requiring high chiral purity.

Basic Information

Product Name	(3S)-(-)-3-(1-Methyl-1H-Indol-3-Yl)Butanenitrile
CAS No.	429689-24-7
Molecular Formula	C₁₃H₁₄N₂
Molecular Weight	198.26 g/mol
Synonyms	(3S)-3-(1-Methyl-1H-indol-3-yl)butyronitrile; (S)-3-(1-Methyl-1H-indol-3-yl)butanenitrile; (-)-3-(1-Methylindol-3-yl)butyronitrile; (S)-(-)-3-(1-Methylindol-3-yl)butyronitrile; 3-(1-Methyl-1H-indol-3-yl)butyronitrile, (3S)-; (S)-3-(1-Methyl-1H-indol-3-yl)butyronitrile; (3S)-3-(1-Methylindol-3-yl)butyronitrile
EINECS	Contact for details

Quality Control

Our (3S)-(-)-3-(1-Methyl-1H-Indol-3-Yl)Butanenitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and production. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and chiral excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.