Description

3-Amino-2,2-difluoro-propionic acid is a specialized fluorinated amino acid derivative, a key building block in advanced organic synthesis. Its unique structure, featuring both amino and difluoromethyl groups on a propionic acid backbone, makes it a valuable precursor for creating novel compounds with enhanced biological activity and stability. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of new active ingredients, including potential protease inhibitors and herbicides.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly protease inhibitors and other biologically active molecules.
• Agrochemical Research: Used in developing new generations of herbicides and plant growth regulators that leverage the stability imparted by fluorine atoms.
• Peptide Mimetics: Serves as a non-natural, fluorinated amino acid analog for creating modified peptides with improved metabolic stability and binding properties.
• Material Science: A precursor for specialty polymers and coatings where fluorine incorporation can enhance chemical resistance and surface properties.
• Chemical Synthesis: A versatile reagent for introducing the difluoromethyl amino acid moiety into more complex molecular architectures in medicinal chemistry.

Basic Information

Product Name	3-Amino-2,2-difluoro-propionic Acid
CAS No.	428452-49-7
Molecular Formula	C₃H₅F₂NO₂
Molecular Weight	125.07 g/mol
Synonyms	2,2-Difluoro-3-aminopropanoic Acid; 3-Amino-2,2-difluoropropanoic Acid; DL-3-Amino-2,2-difluoropropionic Acid; 2,2-Difluoroalanine; 3-Amino-2,2-difluoropropionic Acid; (Rac)-3-Amino-2,2-difluoropropionic Acid
EINECS	Contact for details

Quality Control

Our 3-Amino-2,2-difluoro-propionic acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its acidic nature, keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.