Description

α-Methyl-D-4-Fluorophe is a specialized fluorinated organic compound with a defined chiral center, serving as a critical building block in advanced chemical synthesis. Its precise molecular architecture makes it an essential intermediate for creating high-value, target-specific molecules in regulated industries. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom and chiral methyl group enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and liquid crystals where fluorination imparts desired physical properties.
• Diagnostic Agent Precursor: Potential building block for radiolabeled compounds used in Positron Emission Tomography (PET) imaging.

Basic Information

Product Name	α-Methyl-D-4-Fluorophe
CAS No.	422568-68-1
Molecular Formula	C10H11FO
Molecular Weight	166.19 g/mol
Synonyms	(R)-1-(4-Fluorophenyl)ethanol; (R)-α-Methyl-4-fluorobenzyl alcohol; D-4-Fluoro-α-methylbenzyl alcohol; (R)-4-Fluoro-α-methylbenzenemethanol; (1R)-1-(4-Fluorophenyl)ethan-1-ol; (R)-(-)-1-(4-Fluorophenyl)ethanol; p-Fluoro-α-methylbenzyl alcohol (D-form); Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our α-Methyl-D-4-Fluorophe is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.