Description

2-Pyrrolidineacetonitrile, 1-Acetyl-, (2S)- (9Ci) is a high-value, chiral nitrile derivative of pyrrolidine. This compound matters as a sophisticated building block in asymmetric synthesis, enabling the creation of complex molecules with precise stereochemical control. It is primarily needed by pharmaceutical R&D and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Catalysis: Used as a ligand precursor or a chiral auxiliary in catalytic reactions to induce stereoselectivity.
• Agrochemical Research: Employed in the development of novel, stereospecific pesticides and herbicides.
• Fine Chemical Synthesis: Serves as a versatile building block for creating complex natural products and specialty chemicals.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development in organic and medicinal chemistry.

Basic Information

Product Name	2-Pyrrolidineacetonitrile, 1-Acetyl-, (2S)- (9Ci)
CAS No.	422545-97-9
Molecular Formula	C8H12N2O
Molecular Weight	152.20 g/mol
Synonyms	(S)-1-Acetyl-2-pyrrolidineacetonitrile; (2S)-1-Acetyl-2-pyrrolidineacetonitrile; 1-Acetyl-2-pyrrolidineacetonitrile, (S)-; 2-Pyrrolidineacetonitrile, 1-acetyl-, (2S)-; (S)-2-(1-Acetylpyrrolidin-2-yl)acetonitrile; (S)-1-Acetyl-2-(cyanomethyl)pyrrolidine; (S)-N-Acetyl-2-(cyanomethyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥97% (by HPLC), with specifications tailored for research and process development. Certificates of Analysis (COA) detailing identity, purity, and chiral purity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.