Description

(S)-(+)-(3,5-Dioxa-4-Phospha-Cyclohepta[2,1-A:3,4-A']Dinaphthalen-4-Yl)[(1R)-1-Phenylethyl]Amine is a high-value, chiral organophosphorus ligand with a complex heterocyclic structure, designed for advanced asymmetric synthesis. Its primary value lies in its ability to induce high enantioselectivity in catalytic reactions, a critical factor for producing optically pure intermediates in pharmaceutical and fine chemical manufacturing. This compound is essential for research chemists and process development scientists working in asymmetric hydrogenation, cross-coupling, and other transition metal-catalyzed transformations.

Application

• Asymmetric Catalysis: As a privileged ligand for rhodium, iridium, and ruthenium complexes in enantioselective hydrogenation reactions.
• Pharmaceutical Intermediate Synthesis: For the production of chiral active pharmaceutical ingredients (APIs) requiring high optical purity.
• Fine Chemical Manufacturing: In the synthesis of specialty chemicals, flavors, and fragrances where stereochemistry is crucial.
• Academic & Industrial R&D: As a key reagent for developing new catalytic methodologies and exploring novel reaction pathways.
• Agrochemical Synthesis: For creating chiral compounds used in advanced, selective pesticides and herbicides.
• Material Science Research: Potential use in constructing chiral frameworks for advanced functional materials.

Basic Information

Product Name	(S)-(+)-(3,5-Dioxa-4-Phospha-Cyclohepta[2,1-A:3,4-A']Dinaphthalen-4-Yl)[(1R)-1-Phenylethyl]Amine
CAS No.	422509-53-3
Molecular Formula	C31H24NO2P
Molecular Weight	473.50 g/mol
Synonyms	(S)-(+)-4-[(R)-1-Phenylethylamino]-4H-benzo[d][1,3,2]dioxaphosphinine; (S)-(+)-BINAP-Amine Derivative; (S)-[4-[(1R)-1-Phenylethylamino]-3,5-dioxa-4-phosphacyclohepta[2,1-a:3,4-a']dinaphthalen-4-yl]; Chiral Dioxaphosphinine Ligand; (S,R)-BINOL-Derived Phosphite-Amine Ligand; (S)-(+)-4-((R)-1-Phenylethylamino)-4H-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine; Ligand L*
EINECS	Contact for details

Quality Control

Our (S)-(+)-(3,5-Dioxa-4-Phospha-Cyclohepta[2,1-A:3,4-A']Dinaphthalen-4-Yl)[(1R)-1-Phenylethyl]Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for sensitive catalytic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.