Description

(1Z,3Z)-1,4-Bis(Diphenylphosphino)-1,2,3,4-Tetraphenyl-1,3-Butadiene, Min. 98% Ph4-Nuphos is a high-purity, sterically demanding bidentate phosphine ligand. This compound is valued for its ability to form highly active and selective transition metal complexes, particularly for challenging catalytic transformations. It is essential for researchers and process chemists in pharmaceutical development, fine chemical synthesis, and advanced materials science where precise stereochemical control is paramount.

Application

• Homogeneous Catalysis: As a key ligand in cross-coupling reactions (e.g., Suzuki, Heck, Negishi) and hydrogenation processes.
• Asymmetric Synthesis: Enabling enantioselective C-C and C-X bond formation for the production of chiral intermediates in active pharmaceutical ingredients (APIs).
• Polymerization Catalysis: For the development of novel polyolefins and specialty polymers with controlled architectures.
• Organometallic Chemistry Research: Fundamental studies on metal-ligand interactions and the development of new catalytic systems.
• Fine Chemical Manufacturing: Synthesis of complex, high-value organic molecules where traditional ligands fail.
• Material Science: Fabrication of metal-organic frameworks (MOFs) and catalytic nanomaterials.

Basic Information

Product Name	(1Z,3Z)-1,4-Bis(Diphenylphosphino)-1,2,3,4-Tetraphenyl-1,3-Butadiene, Min. 98% Ph4-Nuphos
CAS No.	420120-75-8
Molecular Formula	C58H44P2
Molecular Weight	802.92 g/mol
Synonyms	Ph4-Nuphos; 1,4-Bis(diphenylphosphino)-1,2,3,4-tetraphenyl-1,3-butadiene; (Z,Z)-1,4-Bis(diphenylphosphino)-1,2,3,4-tetraphenylbuta-1,3-diene; Tetraphenyl-substituted Nuphos Ligand; Bidentate Tetraphenylphosphine Ligand; 420120-75-8; (1Z,3Z)-1,4-Bis(diphenylphosphanyl)-1,2,3,4-tetraphenylbuta-1,3-diene
EINECS	Contact for details

Quality Control

Our Ph4-Nuphos ligand is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic performance. Every lot is characterized by NMR (1H, 31P), HPLC, and elemental analysis to confirm identity and purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality system is designed to meet the stringent requirements of research and development as well as cGMP environments for non-GMP use.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C or as specified on the label or COA. This material is easily oxidized and moisture-sensitive; ensure containers are sealed immediately after use and kept in a cool, dry, well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	Min. 98.0%
31P NMR	Conforms
Solubility Test	Soluble in common organic solvents (THF, Toluene, DCM)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.