Description

D-Tyrosine, o-[(2,6-Dichlorophenyl)Methyl]-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]- is a sophisticated, non-natural amino acid derivative designed for advanced research and development. This compound is a critical building block (Fmoc-protected intermediate) in the synthesis of complex peptides and bioactive molecules, offering precise structural control. It is primarily utilized by pharmaceutical researchers, peptide chemists, and biotechnology companies engaged in drug discovery and proteomics.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an Fmoc-protected tyrosine analog for the controlled assembly of custom peptide sequences.
• Medicinal Chemistry & Drug Discovery: A key intermediate for creating novel peptide-based therapeutics, enzyme inhibitors, and receptor ligands.
• Bioconjugation & Probe Development: Used to introduce a modified tyrosine residue for labeling, cross-linking, or attaching payloads to biomolecules.
• Chemical Biology Research: Tool compound for studying protein-protein interactions, signal transduction pathways, and post-translational modifications.
• Process Development & Scale-Up: Serves as a starting material for the GMP-scale production of active pharmaceutical ingredients (APIs) with specific structural motifs.

Basic Information

Product Name	D-Tyrosine, o-[(2,6-Dichlorophenyl)Methyl]-n-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-
CAS No.	419573-91-4
Molecular Formula	C31H25Cl2NO5
Molecular Weight	562.44 g/mol
Synonyms	Fmoc-D-Tyr(2,6-Cl2Bzl)-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-[(2,6-dichlorophenyl)methyl]-D-tyrosine; Fmoc-D-3-(2,6-Dichlorobenzyloxy)phenylalanine; Fmoc-D-Tyr(2,6-Dichlorobenzyl)-OH; (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-((2,6-dichlorobenzyl)oxy)phenyl)propanoic acid; D-Tyrosine derivative, Fmoc- and 2,6-dichlorobenzyl-protected; Fmoc-D-Tyr(Bzl-2,6-Cl2)-OH
EINECS	Contact for details

Quality Control

Our D-Tyrosine derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (NMR, MS). We provide full traceability and Certificates of Analysis (COA) to support your regulatory and R&D documentation needs. Specifications are aligned with the stringent requirements of pharmaceutical research and process chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% D-isomer
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.