Description

2-Cyano-N-[2-(Trifluoromethyl)Phenyl]Acetamide is a specialized organic compound featuring a cyanoacetamide core substituted with a trifluoromethylphenyl group, making it a valuable fluorinated building block. This molecular architecture is critical for introducing specific physicochemical properties into target molecules, such as enhanced metabolic stability and lipophilicity. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for use in medicinal chemistry and advanced material synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the design and synthesis of advanced herbicides and pesticides, where the trifluoromethyl group can improve biological activity and environmental persistence.
• Material Science Research: Acts as a precursor for developing specialty polymers and liquid crystals, leveraging its rigid aromatic and polar functional groups.
• Chemical Biology Probes: Employed in the construction of molecular probes and inhibitors for studying enzyme function and signal transduction pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs) focused on fluorinated compound libraries.

Basic Information

Product Name	2-Cyano-N-[2-(Trifluoromethyl)Phenyl]Acetamide
CAS No.	419534-37-5
Molecular Formula	C10H7F3N2O
Molecular Weight	228.17 g/mol
Synonyms	2-Cyano-N-(2-(trifluoromethyl)phenyl)acetamide; N-(2-(Trifluoromethyl)phenyl)-2-cyanoacetamide; 2-Cyano-2-(2-(trifluoromethyl)phenylamino)acetic acid amide; Acetamide, 2-cyano-N-[2-(trifluoromethyl)phenyl]-; α-Cyano-2'-(trifluoromethyl)acetanilide; 2-Cyanoacet-2'-trifluoromethylanilide; 419534-37-5; 2-Cyano-N-(α,α,α-trifluoro-o-tolyl)acetamide
EINECS	Contact for details

Quality Control

Our 2-Cyano-N-[2-(Trifluoromethyl)Phenyl]Acetamide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.