Description

Benzenebutanenitrile, 4-Fluoro- (9Ci) is a specialized fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for introducing the 4-fluorophenylbutyronitrile moiety into target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides, fungicides, and pesticides that require fluorinated aromatic components for enhanced activity and stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials due to its aromatic nitrile structure.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions such as Suzuki-Miyaura or Sonogashira couplings to create complex biaryl systems.
• Nitrile Transformation Chemistry: Acts as a starting material for the synthesis of corresponding acids, amides, amines, and tetrazoles.
• Chemical Research & Development: Employed in academic and industrial R&D settings for method development and exploring new fluorination chemistry.

Basic Information

Product Name	Benzenebutanenitrile, 4-Fluoro- (9Ci)
CAS No.	412961-38-7
Molecular Formula	C₁₀H₁₀FN
Molecular Weight	163.19 g/mol
Synonyms	4-Fluorobenzylpropionitrile; 4-Fluorophenylbutyronitrile; 4-Fluoro-γ-phenylbutyronitrile; (4-Fluorophenyl)butyronitrile; 4-Fluorobenzene butanenitrile; 4-Fluoro benzenebutanenitrile; γ-(4-Fluorophenyl)butyronitrile; 4-Fluorobenzyl cyanide, propyl homologue
EINECS	Contact for details

Quality Control

Our Benzenebutanenitrile, 4-Fluoro- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids, strong bases, and strong oxidizing agents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.