Description

3-Amino-3-(2,4-Difluoro-Phenyl)-Propionic Acid is a high-value, non-proteinogenic amino acid derivative featuring a difluorinated phenyl ring, which imparts unique electronic and steric properties. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, particularly for the development of novel active pharmaceutical ingredients (APIs). It is essential for research and production in pharmaceutical chemistry, agrochemicals, and materials science, where its structural motif is leveraged to modulate biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, especially in fluorinated compound libraries targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and plant growth regulators where the difluoro-phenyl moiety enhances bioavailability and environmental stability.
• Peptidomimetics & Bioactive Molecule Design: Incorporated into peptide analogs to improve metabolic stability, membrane permeability, and receptor binding affinity.
• Chemical Biology Probes: Serves as a building block for fluorescent tags, enzyme inhibitors, and other molecular tools used in biochemical research.
• Material Science Precursor: Potential monomer or additive for specialized polymers and advanced materials requiring fluorinated aromatic components.

Basic Information

Product Name	3-Amino-3-(2,4-Difluoro-Phenyl)-Propionic Acid
CAS No.	412925-23-6
Molecular Formula	C9H9F2NO2
Molecular Weight	201.17 g/mol
Synonyms	3-Amino-3-(2,4-difluorophenyl)propanoic acid; 2,4-Difluoro-β-phenyl-β-alanine; (R/S)-3-Amino-3-(2,4-difluorophenyl)propionic acid; β-Amino-2,4-difluorohydrocinnamic acid; 3-(2,4-Difluorophenyl)-3-aminopropionic acid; DL-3-Amino-3-(2,4-difluorophenyl)propanoic acid; 412925-23-6; 3-Amino-3-(2,4-difluorophenyl)propionic acid
EINECS	Contact for details

Quality Control

Our 3-Amino-3-(2,4-Difluorophenyl)-Propionic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and IR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available upon request, detailing all specified parameters to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.