Description

n-Boc-4-Dimethylaminopiperidine is a protected piperidine derivative that serves as a crucial building block in advanced organic synthesis. This compound is valued for its role in introducing the dimethylamino-piperidine moiety, a key structural feature in many bioactive molecules, under mild Boc-protection conditions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Ligand Synthesis: Used in the construction of sophisticated ligands for catalysis and medicinal chemistry applications.
• Agrochemical Research: Serves as a building block for developing novel crop protection agents and pesticides.
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing custom synthesis and scale-up services.
• Academic Research: Utilized in university and institutional labs for methodological development and the synthesis of novel chemical entities.

Basic Information

Item	Details
Product Name	n-Boc-4-Dimethylaminopiperidine
CAS No.	412293-88-0
Molecular Formula	C12H24N2O2
Molecular Weight	228.33 g/mol
Synonyms	1-Boc-4-(Dimethylamino)piperidine; tert-Butyl 4-(dimethylamino)piperidine-1-carboxylate; 4-(Dimethylamino)-1-piperidinecarboxylic Acid 1,1-Dimethylethyl Ester; 4-(N,N-Dimethylamino)piperidine-1-carboxylic Acid tert-Butyl Ester; 1-N-Boc-4-N,N-Dimethylaminopiperidine; Boc-4-DMAP; Boc-DMAP; 4-Dimethylaminopiperidine-1-Boc
EINECS	Contact for details

Quality Control

Our n-Boc-4-Dimethylaminopiperidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing purity, assay, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.