Description

(2S)-2-Pyrrolidinecarbonitrile, 1-[2-[[trans-4-(4-Morpholinylcarbonyl)Cyclohexyl]Amino]Acetyl] is a high-purity, advanced pharmaceutical intermediate featuring a complex, stereochemically defined molecular architecture. This compound is of significant value in modern drug discovery and development, serving as a critical building block for synthesizing novel therapeutic agents. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of small molecule drugs, particularly those targeting neurological and metabolic pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Drug Discovery Scaffold: Used in medicinal chemistry for constructing compound libraries and exploring structure-activity relationships (SAR).
• Protease Inhibitor Synthesis: Serves as a precursor in the synthesis of molecules designed to inhibit specific protease enzymes.
• Neurological & Metabolic Research: Applied in the development of potential therapeutics for central nervous system (CNS) disorders and metabolic diseases.
• Chemical Biology Probe: Utilized as a tool compound to study biological pathways and protein functions in academic and industrial research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	(2S)-2-Pyrrolidinecarbonitrile, 1-[2-[[trans-4-(4-Morpholinylcarbonyl)Cyclohexyl]Amino]Acetyl]
CAS No.	412287-24-2
Molecular Formula	C18H28N4O3
Molecular Weight	348.44 g/mol
Synonyms	1-[2-[[trans-4-(4-Morpholinylcarbonyl)Cyclohexyl]Amino]Acetyl]-(2S)-2-Pyrrolidinecarbonitrile; trans-4-[(2-{[(2S)-2-Cyanopyrrolidin-1-yl]carbonyl}ethyl)amino]cyclohexanecarboxylic Acid Morpholide; (S)-1-(2-((trans-4-(Morpholine-4-carbonyl)cyclohexyl)amino)acetyl)pyrrolidine-2-carbonitrile; UNII-8JQ5607IO5; 8JQ5607IO5; A Chiral Pyrrolidine Derivative; A Morpholine-Cyclohexane Intermediate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) are available upon request, detailing specifications such as chiral purity (enantiomeric excess), chemical purity by HPLC, and residual solvent content. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability. Keep the container tightly sealed in a desiccated environment after opening.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.