Description

1-Pyrrolidineacetamide,3-Hydroxy-,(3R)-(9Ci) is a chiral, hydroxylated pyrrolidine derivative, a high-value building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and bioactive molecules, particularly those targeting the central nervous system. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex chiral APIs.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, especially in neurological and psychiatric therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel bioactive compounds.
• Asymmetric Synthesis: Serves as a versatile chiral scaffold or auxiliary in stereoselective synthesis to construct complex molecular architectures.
• Process Chemistry: Employed in the scale-up and route development for the commercial manufacturing of active pharmaceutical ingredients (APIs).
• Biochemical Research: Potential use as a precursor or inhibitor in enzymatic studies and biochemical pathway investigations.

Basic Information

Product Name	1-Pyrrolidineacetamide,3-Hydroxy-,(3R)-(9Ci)
CAS No.	412278-74-1
Molecular Formula	C6H12N2O2
Molecular Weight	144.17 g/mol
Synonyms	(3R)-3-Hydroxypyrrolidine-1-acetamide; (R)-3-Hydroxypyrrolidine-1-acetamide; 1-Acetamido-3(R)-hydroxypyrrolidine; 3-Hydroxy-1-pyrrolidineacetamide, (R)-; 412278-74-1; (R)-3-Hydroxy-1-pyrrolidineacetamide; 1-Pyrrolidineacetamide, 3-hydroxy-, (3R)-
EINECS	Contact for details

Quality Control

Our 1-Pyrrolidineacetamide,3-Hydroxy-,(3R)-(9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccant in the container.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.