Description

Benzofuran,2,3-Difluoro-2,3-Dihydro-(9Ci) is a specialized fluorinated heterocyclic building block with the CAS registry number 412273-73-5. This compound is valued for its unique molecular scaffold, which incorporates fluorine atoms to modulate electronic properties, lipophilicity, and metabolic stability in advanced synthetic pathways. It is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a precursor in the synthesis of new-generation herbicides, fungicides, and insecticides, where the difluorobenzofuran moiety can enhance biological activity.
• Material Science: Used in the development of organic electronic materials, such as semiconductors for OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Fluorine Chemistry: An essential building block for exploring structure-activity relationships (SAR) in fluorinated compound libraries.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and other transition metal-mediated transformations to create diverse chemical space.

Basic Information

Product Name	Benzofuran,2,3-Difluoro-2,3-Dihydro-(9Ci)
CAS No.	412273-73-5
Molecular Formula	C8H6F2O
Molecular Weight	156.13 g/mol
Synonyms	2,3-Difluoro-2,3-dihydrobenzofuran; 2,3-Difluoro-2,3-dihydro-1-benzofuran; 2,3-Dihydro-2,3-difluorobenzofuran; Benzofuran, 2,3-difluoro-2,3-dihydro-; 412273-73-5; 2,3-Difluorodihydrobenzofuran; Dihydro-2,3-difluorobenzofuran
EINECS	Contact for details

Quality Control

Our Benzofuran,2,3-Difluoro-2,3-Dihydro-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP (current Good Manufacturing Practice) compliance for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.