Description

cis-3-[(tert-Butoxycarbonyl)Amino]Cyclopentane-1-Carboxylic Acid, tert-Butyl (cis-3-Carboxycyclopent-1-Yl)Carbamate is a high-purity, protected amino acid derivative serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a rigid, functionalized cyclopentane scaffold with orthogonal protecting groups, enabling precise and complex molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, metabolic diseases, and anti-infectives.
• Peptidomimetics & Conformationally Restricted Peptides: Used to incorporate constrained, non-natural amino acid residues into peptide backbones to enhance metabolic stability, bioavailability, and receptor selectivity.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with specific stereochemical requirements.
• Ligand & Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis and organocatalysts.
• Chemical Biology Probes: Useful for synthesizing labeled or tagged molecular probes to study biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high stereochemical purity.

Basic Information

Product Name	cis-3-[(tert-Butoxycarbonyl)Amino]Cyclopentane-1-Carboxylic Acid, tert-Butyl (cis-3-Carboxycyclopent-1-Yl)Carbamate
CAS No.	410090-37-8
Molecular Formula	C16H27NO6
Molecular Weight	329.39 g/mol
Synonyms	tert-Butyl N-[(1R,3S)-3-carboxycyclopentyl]carbamate; (1R,3S)-3-[(tert-Butoxycarbonyl)amino]cyclopentane-1-carboxylic acid; (1S,3R)-3-[(tert-Butoxycarbonyl)amino]cyclopentane-1-carboxylic acid; cis-3-Boc-amino-cyclopentanecarboxylic acid; Boc-cis-3-Ac5c-OH; (1S,3R)-3-(Boc-amino)cyclopentanecarboxylic acid; (1R,3S)-3-(Boc-amino)cyclopentanecarboxylic acid; cis-3-(Boc-amino)cyclopentane-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of cis-3-[(tert-Butoxycarbonyl)Amino]Cyclopentane-1-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized and tested against rigorous in-house specifications, with analytical methods including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.