Description

3-Fluoro-4-Biphenylboronic Acid is a high-value organoboron reagent, a key building block in modern synthetic chemistry. Its primary value lies in enabling the precise construction of complex fluorinated biphenyl structures via cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors, where it is used to develop active pharmaceutical ingredients (APIs), liquid crystal materials, and organic electronic components.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid partner for constructing biaryl and heterobiaryl scaffolds under mild conditions.
• Liquid Crystal & OLED Material Synthesis: Used to create fluorinated biphenyl cores that enhance the thermal stability and electro-optical properties of display materials.
• Agrochemical Research: Employed in developing novel fluorinated pesticides and herbicides with improved efficacy and environmental profiles.
• Polymer Chemistry: Acts as a monomer or functionalization agent for creating specialty polymers with tailored properties.
• Chemical Biology & Probe Development: Utilized for labeling and modifying biomolecules to study biological processes.

Basic Information

Product Name	3-Fluoro-4-Biphenylboronic Acid
CAS No.	409108-13-0
Molecular Formula	C12H10BFO2
Molecular Weight	216.02 g/mol
Synonyms	[3-Fluoro-1,1'-biphenyl-4-yl]boronic Acid; (3-Fluoro[1,1'-biphenyl]-4-yl)boronic Acid; 3-Fluoro-4-phenylphenylboronic Acid; 4-Borono-3-fluorobiphenyl; 3-Fluoro-4-biphenylboronic Acid Pinacol Ester (common derivative); 3-F-Biphenyl-4-Boronic Acid; 3-Fluoro-4'-phenylphenylboronic Acid
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-Biphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support development and commercial projects requiring compliance with ICH guidelines and cGMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider storing under an inert atmosphere (argon or nitrogen) to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.