Description

2-(2-Methyl-5-Nitrophenyl)Acetonitrile is a versatile nitrile intermediate characterized by its aromatic methyl and nitro substituents, which are key functional handles for further chemical synthesis. This compound is essential for research and development chemists seeking to build complex molecular architectures, particularly in the pharmaceutical and agrochemical sectors. It serves as a critical precursor for the synthesis of heterocyclic compounds, active pharmaceutical ingredients (APIs), and advanced materials, making it valuable for fine chemical manufacturers and R&D laboratories globally.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those containing indole, quinoline, or other fused heterocyclic systems.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its nitrile group can be transformed into various bioactive functional groups.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, liquid crystals, and organic electronic materials.
• Dye and Pigment Intermediate: Utilized in the synthesis of complex azo dyes and organic pigments due to its nitro and aromatic functionalities.
• Chemical Research & Development: A valuable reagent for methodological studies in organic synthesis, including palladium-catalyzed cross-coupling reactions and cyano-group transformations.

Basic Information

Product Name	2-(2-Methyl-5-Nitrophenyl)Acetonitrile
CAS No.	409082-11-7
Molecular Formula	C9H8N2O2
Molecular Weight	176.17 g/mol
Synonyms	(2-Methyl-5-nitrophenyl)acetonitrile; 2-Methyl-5-nitrobenzyl cyanide; 5-Nitro-o-tolylacetonitrile; α-(2-Methyl-5-nitrophenyl)acetonitrile; 2-(2-Methyl-5-nitrophenyl)ethanenitrile; 2-Methyl-5-nitrobenzeneacetonitrile; 409082-11-7
EINECS	Contact for details

Quality Control

Our 2-(2-Methyl-5-Nitrophenyl)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.