Description

1H-Indene,5,5-Difluorooctahydro-(9Ci) is a specialized fluorinated indane derivative, identified by CAS No. 408528-97-2, valued for its unique structural motif in advanced chemical synthesis. This compound is particularly significant as a versatile building block for introducing difluoromethylene groups into complex molecular architectures. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for incorporating fluorine atoms to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the difluorooctahydroindene core can contribute to enhanced biological activity and environmental profile.
• Material Science Research: Acts as a precursor for novel fluorinated polymers or liquid crystals, exploring properties like chemical resistance and optical characteristics.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex, polycyclic, and fluorinated organic molecules for various applications.
• Ligand and Catalyst Development: Potential use in designing novel chiral ligands or organocatalysts due to its rigid, polycyclic structure.

Basic Information

Product Name	1H-Indene,5,5-Difluorooctahydro-(9Ci)
CAS No.	408528-97-2
Molecular Formula	C9H12F2
Molecular Weight	158.19 g/mol
Synonyms	5,5-Difluorooctahydro-1H-indene; Octahydro-5,5-difluoro-1H-indene; 1H-Indene, octahydro-5,5-difluoro-; 5,5-Difluoroperhydroindene; Difluorooctahydroindane
EINECS	Contact for details

Quality Control

Our 1H-Indene,5,5-Difluorooctahydro-(9Ci) is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including NMR, GC, and HPLC, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee it meets your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong alkalis and other incompatible materials as indicated by its fluoride/strong alkali property. For long-term storage, consider keeping the container under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.