Description

3-Chloro-5-Methoxycarbonyl-Phenyl-Boronic Acid Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative, widely recognized for its stability and utility in advanced organic synthesis. This compound serves as a crucial protected boronic acid building block, enabling precise cross-coupling reactions to construct complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific chlorinated aromatic motifs.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes and inhibitors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and complex targets on a commercial scale.
• Academic & Industrial R&D: A fundamental reagent for methodological development in synthetic organic chemistry and catalysis studies.

Basic Information

Product Name	3-Chloro-5-Methoxycarbonyl-Phenyl-Boronic Acid Pinacol Ester
CAS No.	408492-29-5
Molecular Formula	C14H18BClO4
Molecular Weight	296.55 g/mol
Synonyms	(3-Chloro-5-(methoxycarbonyl)phenyl)boronic acid pinacol ester; 3-Chloro-5-(methoxycarbonyl)benzeneboronic acid pinacol ester; Methyl 3-chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; 2-(3-Chloro-5-methoxycarbonylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Benzoic acid, 3-chloro-5-(methoxycarbonyl)-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl ester; 408492-29-5; Boronic acid, B-[3-chloro-5-(methoxycarbonyl)phenyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and commercial use. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and GC to verify identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing batch-specific results are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This material is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.