Description

Naphthalene, 6-Ethynyl-1,2,3,4-Tetrahydro- is a specialized tetralin derivative featuring an ethynyl substituent, making it a valuable synthetic intermediate for advanced organic chemistry. This compound is critical for constructing complex molecular architectures, particularly in pharmaceutical research and materials science. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring precise functional group manipulation.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its fused ring system for bioactive molecule design.
• Ligand & Catalyst Development: Serves as a precursor for creating sophisticated ligands in transition metal catalysis and organometallic chemistry.
• Material Science Precursor: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers due to its rigid, conjugated backbone.
• Academic & Industrial R&D: A versatile tool for methodological studies in cross-coupling reactions, cycloadditions, and other synthetic transformations.

Basic Information

Product Name	Naphthalene, 6-Ethynyl-1,2,3,4-Tetrahydro-
CAS No.	408320-46-7
Molecular Formula	C₁₂H₁₂
Molecular Weight	156.22 g/mol
Synonyms	6-Ethynyl-1,2,3,4-tetrahydronaphthalene; 6-Ethynyltetralin; 1,2,3,4-Tetrahydro-6-ethynylnaphthalene; 6-Ethynyl-1,2,3,4-tetrahydronaphthalene; 6-Ethynyltetrahydronaphthalene; 408320-46-7 (CAS); 6-Ethynyl-1,2,3,4-tetrahydro-naphthalene
EINECS	Contact for details

Quality Control

Our Naphthalene, 6-Ethynyl-1,2,3,4-Tetrahydro- is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with relevant guidelines for advanced intermediates, and specifications can be aligned with customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from oxidizing agents and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.