Description

2-Pentanone, 3-Fluoro-4-Hydroxy- (9Ci) is a specialized fluorinated ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both fluorine and hydroxyl substituents, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a fluorinated building block for electronic chemicals used in display and lighting technologies.
• Advanced Polymer Modification: Employed to introduce fluorine and hydroxyl functionality into polymer chains, altering surface properties and chemical resistance.
• Organic Synthesis & Process Chemistry: A versatile reagent for constructing complex organic frameworks in academic and industrial research laboratories.
• Fluorine Chemistry Research: Critical for studying structure-activity relationships (SAR) and developing new fluorination methodologies.

Basic Information

Product Name	2-Pentanone, 3-Fluoro-4-Hydroxy- (9Ci)
CAS No.	408306-68-3
Molecular Formula	C5H9FO2
Molecular Weight	120.12 g/mol
Synonyms	3-Fluoro-4-hydroxypentan-2-one; 4-Hydroxy-3-fluoropentan-2-one; 3-Fluoro-4-hydroxypentan-2-one (9CI); 2-Pentanone, 3-fluoro-4-hydroxy-; 3-Fluoro-4-hydroxy-2-pentanone; 3-Fluoro-4-hydroxypentan-2-one; 408306-68-3 (CAS)
EINECS	Contact for details

Quality Control

Our 2-Pentanone, 3-Fluoro-4-Hydroxy- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.