Description

Pth (7-84) (Human) is a specific fragment of the human parathyroid hormone, a critical peptide involved in calcium and phosphate homeostasis. This high-purity reference standard is essential for research and development in endocrinology and metabolic bone disease studies. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers for assay development, bioactivity testing, and quality control of related therapeutic products.

Application

• Biomedical Research: Used as a reference standard in studies of calcium metabolism, bone remodeling, and renal function.
• Assay Development & Validation: Critical for calibrating immunoassays (e.g., ELISA, RIA) and bioassays designed to detect PTH or its fragments.
• Drug Discovery & Screening: Serves as a key reagent in high-throughput screening for compounds targeting the PTH receptor pathway.
• Quality Control: Employed as a system suitability standard in the manufacturing and QC testing of PTH-based therapeutics and diagnostic kits.
• Metabolic Disease Modeling: Used in *in vitro* and *in vivo* models to study disorders like hyperparathyroidism and hypoparathyroidism.

Basic Information

Product Name	Pth (7-84) (Human)
CAS No.	406610-86-4
Molecular Formula	C390H637N115O118S2
Molecular Weight	Approx. 8830.2 g/mol
Synonyms	Parathyroid Hormone (7-84), Human; PTH (7-84); hPTH (7-84); Parathyrin (7-84); Parathormone fragment (7-84); PTH Fragment 7-84; N-terminal truncated PTH; PTH (7-84) human fragment
EINECS	Contact for details

Quality Control

Our Pth (7-84) (Human) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and endotoxin testing. Certificates of Analysis (COA) detailing all specifications and test results are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.