Description

1-Bromo-4-Methoxy-2,3-Difluorobenzene is a high-value, multi-functional aromatic building block essential for advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules with precise electronic and steric properties. This compound is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluorinated aryl ether scaffold.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the bromine atom serves as a handle for further functionalization.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, contributing to the molecular architecture of display and lighting components.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and monomers, imparting specific properties like thermal stability or chemical resistance.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Heck, Buchwald-Hartwig) to create complex biaryl structures.
• Chemical Research & Development: A versatile reagent for exploring new synthetic pathways and creating libraries of compounds for screening in various industries.

Basic Information

Product Name	1-Bromo-4-Methoxy-2,3-Difluorobenzene
CAS No.	406482-22-2
Molecular Formula	C7H5BrF2O
Molecular Weight	223.02 g/mol
Synonyms	2,3-Difluoro-4-methoxybromobenzene; 4-Bromo-2,3-difluoroanisole; 2,3-Difluoro-4-methoxy-1-bromobenzene; Benzene, 1-bromo-4-methoxy-2,3-difluoro-; 4-Methoxy-2,3-difluorobromobenzene; 1-Bromo-2,3-difluoro-4-methoxybenzene; 406482-22-2
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Methoxy-2,3-Difluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.