Description

2-Bromo-N-(3,5-difluorophenyl)acetamide is a specialized halogenated acetamide derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular structure, which incorporates both bromine and fluorine atoms, making it a versatile intermediate for constructing complex molecules. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the difluorophenyl moiety for enhanced biological activity and metabolic stability.
• Material Science: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers with unique thermal or chemical resistance properties.
• Chemical Biology: Employed as a probe or labeling reagent in biochemical studies due to the reactive bromoacetamide group.
• Organic Synthesis: A versatile building block for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create complex biaryl structures.

Basic Information

Product Name	2-Bromo-N-(3,5-difluorophenyl)acetamide
CAS No.	405937-75-9
Molecular Formula	C8H6BrF2NO
Molecular Weight	250.04 g/mol
Synonyms	N-(3,5-Difluorophenyl)-2-bromoacetamide; 2-Bromoacet-3',5'-difluoroanilide; Acetamide, 2-bromo-N-(3,5-difluorophenyl)-; 2-Bromo-2',4'-difluoroacetanilide; α-Bromo-3,5-difluoroacetanilide; Bromoacetic acid (3,5-difluoroanilide); BRD-K94255320
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request, providing full traceability and supporting your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.