Description

2-Azetidinone,1-(2-Methyl-1-Oxo-2-Propenyl)-(9Ci) is a specialized β-lactam derivative, a key structural motif in medicinal chemistry. This compound matters as a versatile and high-value chemical building block for the synthesis of novel pharmaceutical intermediates and active ingredients. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries, where it serves as a precursor for complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel β-lactam antibiotics and other bioactive molecules targeting bacterial infections.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in drug discovery programs, particularly for exploring new modes of action.
• Organic Synthesis Building Block: Used in advanced organic transformations, including ring-opening and functionalization reactions, to create complex heterocyclic compounds.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs) under cGMP conditions.
• Bioconjugation Chemistry: Potential use in the development of targeted drug delivery systems and antibody-drug conjugates (ADCs) due to its reactive carbonyl group.
• Academic & Institutional Research: Utilized in universities and research institutes for studying β-lactam reactivity and developing new synthetic methodologies.

Basic Information

Product Name	2-Azetidinone,1-(2-Methyl-1-Oxo-2-Propenyl)-(9Ci)
CAS No.	405114-51-4
Molecular Formula	C7H9NO2
Molecular Weight	139.15 g/mol
Synonyms	1-(2-Methylacryloyl)azetidin-2-one; 1-Methacryloyl-2-azetidinone; 2-Azetidinone, 1-(2-methyl-1-oxo-2-propen-1-yl)-; N-Methacryloyl-2-azetidinone; 1-(2-Methylprop-2-enoyl)azetidin-2-one; β-Lactam, N-methacryloyl derivative; Azetidin-2-one, 1-(2-methylacryloyl)-
EINECS	Contact for details

Quality Control

Our 2-Azetidinone,1-(2-Methyl-1-Oxo-2-Propenyl)-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC and NMR analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications in cGMP environments and advanced research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.