Description

1-(4-Fluorophenyl)Cyclobutanecarbonitrile is a versatile and high-value organic building block featuring a cyclobutane ring and a fluorinated aromatic system. This compound is essential for advanced organic synthesis, particularly in the development of novel pharmacologically active molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for creating new chemical entities and fine chemical intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a sophisticated ligand precursor in organometallic chemistry and asymmetric catalysis.
• Material Science: Employed in the research of advanced polymers and liquid crystals, where the rigid cyclobutane and fluorophenyl groups impart unique physical properties.
• Chemical Biology Probes: Utilized as a scaffold for creating fluorescent tags or molecular probes to study biological systems.
• Custom Synthesis: A critical starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	1-(4-Fluorophenyl)Cyclobutanecarbonitrile
CAS No.	405090-30-4
Molecular Formula	C11H10FN
Molecular Weight	175.20 g/mol
Synonyms	4-Fluorophenylcyclobutanecarbonitrile; 1-(4-Fluorophenyl)cyclobutanecarbonitrile; 1-(p-Fluorophenyl)cyclobutanecarbonitrile; Cyclobutanecarbonitrile, 1-(4-fluorophenyl)-; 4-Fluorophenyl cyclobutanecarbonitrile; p-Fluorophenylcyclobutanecarbonitrile; 1-(4-Fluorophenyl)-1-cyanocyclobutane
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorophenyl)Cyclobutanecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.