Description

Bzl-Gln-Ome Hcl is a protected glutamine derivative, specifically the benzyl ester hydrochloride salt of glutamine methyl ester. This compound serves as a crucial building block (amino acid derivative) in the synthesis of complex peptides and pharmaceutical intermediates. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for drug discovery and development projects.

Application

• Peptide Synthesis: A key protected amino acid precursor in solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Intermediates: Used in the research and production of active pharmaceutical ingredients (APIs) and therapeutic peptides.
• Bioconjugation: Serves as a modified amino acid for creating custom peptide-protein conjugates or labeled biomolecules.
• Chemical Biology Research: Employed in studying enzyme mechanisms, protein-protein interactions, and metabolic pathways.
• Prodrug Development: Potential use in designing prodrugs where the protecting groups allow for controlled release.
• Fine Chemical Manufacturing: Acts as a specialized intermediate for synthesizing high-value, complex organic molecules.

Basic Information

Product Name	Bzl-Gln-Ome Hcl
CAS No.	402929-52-6
Molecular Formula	C14H21N3O4 • HCl
Molecular Weight	331.79 g/mol (Free base: 295.33 g/mol)
Synonyms	L-Glutamine, N2-[(benzyloxy)carbonyl]-, methyl ester, hydrochloride; Z-Gln-OMe • HCl; N-Carbobenzoxy-L-glutamine methyl ester hydrochloride; Cbz-L-glutamine methyl ester hydrochloride; (2S)-2-{[(Benzyloxy)carbonyl]amino}-4-carbamoylbutanoic acid methyl ester hydrochloride; Nα-Cbz-L-glutamine methyl ester hydrochloride; Z-L-Glutamine methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Bzl-Gln-Ome Hcl is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and Mass Spectrometry. We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]D20	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.