Description

2-(Diphenylphosphino)-2'-Methoxybiphenyl is a specialized monodentate phosphine ligand with a biphenyl backbone. This compound matters for its role in facilitating challenging cross-coupling reactions, offering a balance of steric bulk and electron-donating properties. It is primarily needed by researchers and process chemists in the pharmaceutical and advanced materials sectors for catalyst development and fine chemical synthesis.

Application

• Catalyst Ligand in Cross-Coupling Reactions: A key component in palladium-catalyzed Suzuki-Miyaura, Buchwald-Hartwig, and other C-C/C-N bond-forming reactions.
• Pharmaceutical Intermediate Synthesis: Enables the construction of complex heterocycles and active pharmaceutical ingredients (APIs) under mild conditions.
• Material Science Research: Used in the development of organic light-emitting diodes (OLEDs) and conductive polymers.
• Asymmetric Catalysis: Serves as a precursor or auxiliary ligand for creating chiral catalysts.
• Academic & Industrial R&D: A valuable tool for methodology development and exploring new catalytic transformations in laboratory settings.

Basic Information

Product Name	2-(Diphenylphosphino)-2'-Methoxybiphenyl
CAS No.	402822-70-2
Molecular Formula	C25H21OP
Molecular Weight	368.41 g/mol
Synonyms	2-(Diphenylphosphino)-2'-methoxy-1,1'-biphenyl; 2'-Methoxy-2-(diphenylphosphino)biphenyl; MeO-Biphenyl-Phos; (2'-Methoxy[1,1'-biphenyl]-2-yl)diphenylphosphine; DavePhos (common name); Ligand for Buchwald-Hartwig amination; Monodentate biaryl phosphine ligand
EINECS	Contact for details

Quality Control

Our 2-(Diphenylphosphino)-2'-Methoxybiphenyl is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. This material is easily oxidized and light-sensitive.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.