Description

(S) Fty720 Phosphate CAS NO 402616-26-6 is the biologically active phosphate ester of Fingolimod, a potent sphingosine-1-phosphate (S1P) receptor modulator. This high-purity compound is a critical reference standard and active pharmaceutical ingredient (API) intermediate for advanced pharmaceutical research and development. It is essential for scientists and manufacturers in the pharmaceutical and biotechnology sectors working on immunomodulatory therapies, particularly for conditions like multiple sclerosis.

Application

• Pharmaceutical Reference Standard: Serves as a primary analytical standard for quality control and method validation in API and finished drug product manufacturing.
• Active Pharmaceutical Ingredient (API) Intermediate: A key synthetic precursor in the production of Fingolimod hydrochloride and related therapeutic agents.
• Biomedical Research: Used in in vitro and in vivo studies to investigate S1P receptor biology, lymphocyte trafficking, and autoimmune disease mechanisms.
• Drug Discovery & Development: Employed in screening assays and preclinical development of novel immunomodulators and S1P receptor-targeted therapies.
• Process Chemistry & Scale-up: Utilized for optimizing synthetic routes and scaling up production processes under GMP conditions.

Basic Information

Product Name	(S) Fty720 Phosphate
CAS No.	402616-26-6
Molecular Formula	C23H36NO6P
Molecular Weight	453.51 g/mol
Synonyms	(S)-Fingolimod Phosphate; (2S)-2-Amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol Dihydrogen Phosphate Ester; FTY 720-P; (S)-FTY720 Phosphate; (S)-Fingolimod (FTY720) Phosphate; AAL 151; AAL-151; GILENYA® (Fingolimod) API Intermediate
EINECS	Contact for details

Quality Control

Our (S) Fty720 Phosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation by IR and MS. We provide full traceability and Certificates of Analysis (COA) detailing all specifications. Production can be aligned with ICH guidelines and current Good Manufacturing Practice (cGMP) standards for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. The product is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.