Description

tert-Butyl trans-4-(n-Methoxy-n-Methylcarbamoyl)Cyclohexylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and functional groups. This compound is of significant value in medicinal chemistry as a key building block for the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic pathways. It is primarily required by R&D laboratories and production facilities in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially in medicinal chemistry programs.
• API Synthesis: Serves as a key chiral building block for constructing complex Active Pharmaceutical Ingredients (APIs) with defined stereochemistry.
• Protease Inhibitor Research: Used in the research and development of protease inhibitors, a major class of drugs for treating various diseases.
• Peptidomimetic Chemistry: Integral to the synthesis of peptidomimetics, which are molecules that mimic peptides but with enhanced stability and bioavailability.
• Chemical Biology Probes: Employed in the creation of specialized probes for studying enzyme function and biological pathways.
• Process Development & Scale-up: Utilized in process chemistry for optimizing and scaling synthetic routes from laboratory to pilot and commercial production.

Basic Information

Product Name	tert-Butyl trans-4-(n-Methoxy-n-Methylcarbamoyl)Cyclohexylcarbamate
CAS No.	400898-92-2
Molecular Formula	C15H28N2O4
Molecular Weight	300.40 g/mol
Synonyms	trans-4-[(tert-Butoxycarbonyl)amino]cyclohexanecarboxylic acid N-methoxy-N-methylamide; Boc-trans-4-amino-cyclohexanecarboxylic acid N-methoxy-N-methylamide; tert-Butyl (trans-4-((methoxy(methyl)carbamoyl)cyclohexyl)carbamate; N-Boc-trans-4-aminocyclohexanecarboxylic acid Weinreb amide; trans-N-Boc-4-aminocyclohexanecarboxylic acid N,O-dimethylhydroxylamide; Boc-4-Amino-trans-cyclohexanecarboxylic acid N-methoxy-N-methyl amide; Weinreb amide of Boc-trans-4-aminocyclohexanecarboxylic acid
EINECS	Contact for details

Quality Control

Our tert-Butyl trans-4-(n-Methoxy-n-Methylcarbamoyl)Cyclohexylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and isomeric purity suitable for demanding pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Isomeric Purity (Chiral HPLC)	≥ 99.0% (trans isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.