Description

7 β - Amino - 3 - [4 - Pyridyl - 2 - Thiazole Sulfur Radical ] - 3 - Cephem - 4 - Carboxylic Acid ·2Hcl is a high-purity, advanced pharmaceutical intermediate, specifically a cephalosporin derivative. This compound is critical for the research and development of next-generation β-lactam antibiotics, offering a key structural motif for targeting resistant bacterial strains. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in antimicrobial drug discovery and synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel cephalosporin-class antibiotics.
• Antimicrobial Research: Used in biochemical research to study structure-activity relationships (SAR) against Gram-positive and Gram-negative bacteria.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the development and scale-up of new antibacterial drug candidates.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for specialized chemical entities.
• Academic & Institutional Research: A valuable reagent for universities and research institutes focusing on medicinal chemistry and microbiology.

Basic Information

Product Name	7 β - Amino - 3 - [4 - Pyridyl - 2 - Thiazole Sulfur Radical ] - 3 - Cephem - 4 - Carboxylic Acid ·2Hcl
CAS No.	400827-70-5
Molecular Formula	C16H15N5O4S2 · 2HCl
Molecular Weight	502.82 g/mol (Free base: 405.45 g/mol)
Synonyms	7β-Amino-3-[(4-pyridyl-2-thiazolyl)thio]-3-cephem-4-carboxylic acid dihydrochloride; 7β-Amino-3-(4-pyridin-2-yl-1,3-thiazol-2-yl)sulfanyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride; Cephalosporin derivative intermediate; 7-ACA pyridylthiazole derivative; (6R,7R)-7-Amino-3-[(4-pyridin-2-yl-1,3-thiazol-2-yl)sulfanyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid dihydrochloride
EINECS	Contact for details

Quality Control

Our 7 β - Amino - 3 - [4 - Pyridyl - 2 - Thiazole Sulfur Radical ] - 3 - Cephem - 4 - Carboxylic Acid ·2Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and handled under conditions that minimize exposure to ambient light and humidity to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.