Description

Boc-D-Pyr-Obzl is a protected amino acid derivative widely used as a crucial building block in peptide synthesis. This compound matters for its role in introducing the D-proline analog with orthogonal protecting groups, enabling precise control over stereochemistry and reaction sequences in complex molecule assembly. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and other bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of D-configured proline analogs into peptide chains.
• Solution-Phase Peptide Chemistry: Used in the synthesis of complex peptides and small proteins where solution-phase methods are preferred.
• Pharmaceutical Research & Development: Serves as a critical raw material in the R&D of peptide-based drugs targeting various diseases.
• Peptidomimetic Design: Employed to create stable, bioavailable mimics of natural peptides for drug discovery programs.
• Bioconjugation: Can be utilized to attach peptide sequences to other molecules, such as antibodies or polymers, for creating targeted therapies or diagnostics.
• Academic Research: Used in university and institutional labs for studying peptide structure-activity relationships and developing new synthetic methodologies.

Basic Information

Product Name	Boc-D-Pyr-Obzl
CAS No.	400626-71-3
Molecular Formula	C₁₈H₂₅NO₅
Molecular Weight	335.40 g/mol
Synonyms	(2S)-1-[(2-Methylpropan-2-yl)oxycarbonyl]-5-oxopyrrolidine-2-carboxylic acid benzyl ester; Boc-D-5-oxoproline benzyl ester; Boc-D-pyroglutamic acid benzyl ester; tert-Butoxycarbonyl-D-pyroglutamic acid benzyl ester; Boc-D-Pyr-OBzl; Boc-D-Pyr(Bzl)-OH; (S)-1-((tert-Butoxycarbonyl)-5-oxopyrrolidine-2-carboxylic acid benzyl ester
EINECS	Contact for details

Quality Control

Our Boc-D-Pyr-Obzl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.