Description

3-Amino-2-(4-Fluorophenyl)Pyrido[1,2-A][1,3]Benzimidazole-4-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in developing new therapeutic agents, particularly in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting specific enzymatic pathways.
• Organic Synthesis Building Block: Utilized in research and development for constructing novel heterocyclic compounds with potential biological activity.
• Medicinal Chemistry Research: A key scaffold for structure-activity relationship (SAR) studies in drug discovery programs focused on benzimidazole and pyridine derivatives.
• Biochemical Reagent: Used in laboratory settings for studying molecular interactions and as a standard in analytical method development.
• Material Science Research: Investigated for potential applications in creating organic electronic materials due to its conjugated π-system.

Basic Information

Product Name	3-Amino-2-(4-Fluorophenyl)Pyrido[1,2-A][1,3]Benzimidazole-4-Carbonitrile
CAS No.	400085-94-1
Molecular Formula	C19H12FN5
Molecular Weight	329.33 g/mol
Synonyms	3-Amino-2-(4-fluorophenyl)pyrido[1,2-a]benzimidazole-4-carbonitrile; 2-(4-Fluorophenyl)-3-aminopyrido[1,2-a]benzimidazole-4-carbonitrile; 4-Cyano-3-amino-2-(4-fluorophenyl)pyrido[1,2-a]benzimidazole; PFAPBC; CAS 400085-94-1; 3-Amino-2-(p-fluorophenyl)pyrido[1,2-a]benzimidazole-4-carbonitrile
EINECS	Contact for details

Quality Control

Our production of 3-Amino-2-(4-Fluorophenyl)Pyrido[1,2-A][1,3]Benzimidazole-4-Carbonitrile adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All materials are subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.