Description

3-Bromo-4-(4-Fluorophenyl)-4-Oxobutanoic Acid is a high-purity, versatile brominated keto acid derivative. This compound serves as a critical synthetic intermediate, valued for its reactive bromine and ketone functional groups which enable complex molecular transformations. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the fluorophenyl moiety for bioactivity.
• Organic Synthesis: Serves as a versatile precursor for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Material Science: Potential monomer or cross-linking agent in the development of specialty polymers with unique properties.

Basic Information

Product Name	3-Bromo-4-(4-Fluorophenyl)-4-Oxobutanoic Acid
CAS No.	49780-08-7
Molecular Formula	C10H8BrFO3
Molecular Weight	275.07 g/mol
Synonyms	3-Bromo-4-(4-fluorobenzoyl)butanoic acid; 4-(4-Fluorobenzoyl)-3-bromobutanoic acid; 3-Bromo-4-(4-fluorophenyl)-4-oxobutanoic acid; γ-Bromo-β-(4-fluorobenzoyl)propionic acid; Butanoic acid, 3-bromo-4-(4-fluorophenyl)-4-oxo-; 4-Oxo-4-(4-fluorophenyl)-3-bromobutanoic acid; 3-Bromo-4-(4-fluorobenzoyl)butyric acid
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-(4-Fluorophenyl)-4-Oxobutanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.