Description

(4-Trifluoromethylphenylamino)Methylenemalonic Acid Diethyl Ester is a specialized organic building block featuring a trifluoromethylphenylamino group and a malonic ester moiety. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical and advanced material sectors for constructing novel heterocyclic compounds and active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging the biological activity of the trifluoromethyl group.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and functional materials with unique optical or electronic properties.
• Organic Synthesis Reagent: Employed in multi-step synthetic routes for constructing complex heterocycles, such as quinolones and pyrimidines, via cyclocondensation reactions.
• Chemical Biology Probe Development: Utilized as a scaffold for creating molecular probes to study enzyme mechanisms and biological pathways.

Basic Information

Product Name	(4-Trifluoromethylphenylamino)Methylenemalonic Acid Diethyl Ester
CAS No.	49713-39-5
Molecular Formula	C15H16F3NO4
Molecular Weight	331.29 g/mol
Synonyms	Diethyl 2-[(4-Trifluoromethylphenyl)amino]methylenemalonate; Diethyl (4-Trifluoromethylphenylamino)methylenemalonate; Ethyl (4-Trifluoromethylphenylamino)methylenemalonate; 2-[(4-Trifluoromethylphenyl)amino]methylenemalonic Acid Diethyl Ester; (4-Trifluoromethylphenylamino)methylenemalonic Acid Ethyl Ester; α-[(4-Trifluoromethylphenyl)amino]methylene Malonic Acid Diethyl Ester; CAS 49713-39-5
EINECS	Contact for details

Quality Control

Our (4-Trifluoromethylphenylamino)Methylenemalonic Acid Diethyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.